First of all you must determine "What kind of Depression"
The effectiveness of any particular medical approach depends on what type of depression a patient has.
MAJOR DEPRESSION, has symptons that are severe enough to last six months or longer if untreated and that impact on most aspects of a sufferer's life.
BIPOLAR DISORDER, is also known as manic depression. Sufferers may experiences emotional extremes that careen between prolonged episodes of intense hyperactivity and devastating lows (depression)
DYSTHYMIA, although not as disabling as major depression, has depressive symptons that make it difficult for patient to function normally Some may also experience intermittent periods of major depression.
POSTPARTUM DEPRESSION, is a debiliating emotional condition that affects many mothers after they give birth.
SEASONAL AFFECTIVE DISORDER, likely occurs as a result of a lack of sunlight during autumn winter. It usually clears up during spring and summer.
Above all, never under estimate the power of prayer - the depressed ones may wonder how God can help them when they experience distressing emotions.